The Apostolic Exarchate of Ujjain was erected as the Eparchy of Ujjain on February 26, 1977 by Pope Paul VI with the Apostolic Letter “Qui divino consilio”, Msgr. John Perumattam was appointed its first Bishop. He was consecrated bishop by His Excellency late Mar Sebastian Vayalil, bishop of Palai, on May 15, 1977 and he took canonical possession of the office on 3 July 1977. On 5th June 1998, Pope John Paul II accepted his resignation and Father Sebastian Vadakel was nominated the second bishop of Ujjain. He was consecrated bishop on 8th September 1998 and he took canonical possession of the see on the same day.

The syro-Malabar mission Eparchy of Ujjain has, in the past 35 Years of its existence, made ernest efforts to reach the Good News to all the people in the eparchy and to share the love of Jesus with them in various ways. At present there are, in the eparchy, 38mission stations with resident priests and religious sisters. Besides, there are a number of ecclesiastical institutions and apostolates that help in sharing the good news with the people in the Eparchy.